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Injecting Adderall | Effects & Dangers Of Amphetamine Abuse

Published on April 27, 2021
Shooting Up Adderall | The Dangers Of Injecting Adderall

Adderall, a brand-name medication containing dextroamphetamine and amphetamine, can be abused in several ways, including injection.

However, modifying drugs for injection abuse is hazardous and can cause lasting physical harm and heighten the risk of dependence and addiction.

Injection Adderall Abuse

Adderall is available in an immediate-release tablet (Adderall) and an extended-release capsule (Adderall XR) that provides longer-lasting effects.

In either case, this controlled substance is typically prescribed to treat attention deficit hyperactivity disorder (ADHD) and sleep disorders such as narcolepsy.

In higher doses, however, the drug can be abused to improve concentration and energy, suppress appetite, or induce a euphoric stimulant high similar to methamphetamine.

Shooting Up Adderall

Because tablets and capsules need to be broken down in the digestive system before they can be absorbed into the bloodstream, these medications are sometimes crushed into a fine powder, mixed with water, filtered, and injected directly into a vein. 

This process of shooting up Adderall delivers the full dose of the drug directly into the bloodstream, greatly speeding and intensifying its effect.

Effects Of Adderall Abuse

Short-term effects of Adderall abuse include:

  • a flash or rush of euphoria
  • reduced appetite
  • hyperactivity
  • improved confidence
  • reduced inhibition
  • a sense of clarity or improved thinking
  • talkativeness
  • irritability
  • behavioral changes, including mania or psychosis

When injected, these effects begin almost immediately but only last several minutes, often prompting individuals to take another hit.

Long-term Adderall abuse is known to cause a variety of harmful side effects including:

  • unhealthy weight loss
  • serious heart dysfunction
  • memory issues
  • increased risk of heart attack or stroke
  • aggressive tendencies
  • depression
  • increased risk of suicide
  • restlessness
  • muscle tremors
  • sleep issues
  • tooth decay

Dangers & Health Risks Of Injecting Adderall

Injecting Adderall or other pill-based medications exposes you to a number of severe health risks, including:


The majority of those who abuse drugs by injection develop scarring around injection sites, known as track marks. Track marks can be permanent, serving as a lifelong reminder of past drug abuse.

Vein Damage

The process of physically injecting Adderall can damage or collapse veins and blood vessels, especially if injection sites become infected or if the injections are performed with poor technique. And the introduction of fillers and binders suspended in the solution only increases this risk.

As a result, the veins of the arms may become too scarred and damaged to use. This can prompt individuals to switch to other, risker injection sites in the neck or femoral veins.


Whenever needles, water, and filters are used (or re-used) for intravenous injection outside of a sterile medical environment, infections become extremely likely. 

These can include extremely dangerous infections like HIV/AIDS, hepatitis B, and hepatitis C, as well as harmful skin and vein infections resulting in abscesses or open wounds around injection sites.

Heart Damage

Injecting Adderall intravenously can cause endocarditis, or inflammation of the interior lining of the heart. This condition can lead to serious physical harm and is potentially life-threatening.

The effects of the drug can also disrupt the cardiovascular system in other ways, resulting in arrhythmia (irregular heartbeat), cardiac arrest (heart attack), hypertension (high blood pressure), hypotension (low blood pressure), and poor overall circulation (blood flow).

Overdose & Death

While overdosing on Adderall alone is unlikely, intravenous use can introduce such a large dose directly into the bloodstream that adverse reactions, including overdose, become much more likely.

Adverse effects, including Adderall overdose, are also more likely when Adderall abuse is mixed with recreational abuse of other drugs, including alcohol, or if Adderall is abused by someone with a heart condition.

Dependence & Addiction

If Adderall is used as prescribed there is a very low likelihood that you will become seriously dependent on the medication or addicted to it.

However, increasing the dose, taking it for longer periods of time than prescribed, or using it through injection increases the risk of dependence and the odds that your misuse of Adderall will become compulsive.

Treating Stimulant Use Disorder

Adderall abuse is common and often impacts those who wouldn’t typically be suspected of abusing prescription drugs. If you or a loved one are abusing Adderall, professional and compassionate care is available to help. 

At Ark Behavioral Health, your treatment program will be highly personalized and tailored to your needs, and can be conducted in either an inpatient or outpatient basis.

Adderall addiction treatment generally includes medical detox, cognitive behavioral therapy, peer support groups, and other supportive services.

Please contact us today to learn more.

Written by Ark Behavioral Health Editorial Team
This page does not provide medical advice.

National Harm Reduction Coalition - Potential Health Complications of Injection Drug Use
National Institute on Drug Abuse (NIDA) - Prescription Stimulants DrugFacts
National Library of Medicine: MedlinePlus - Substance use - amphetamines

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