New Buprenorphine Prescribing Guidelines | What It Means For Opioid Addiction Treatment

Buprenorphine is a medication used to treat opioid addiction. Available as a pill or film that dissolves under the tongue, it reduces withdrawal symptoms and cravings.
Since the FDA approved the drug in 2002, many people have struggled to get a prescription for it. On April 27th, 2021, the United States government released new prescribing guidelines that aim to make buprenorphine more accessible.
What Are The New Buprenorphine Prescribing Guidelines?
In the past, only doctors could prescribe buprenorphine. The new guidelines extend this ability to a variety of other health workers, including:
- nurse practitioners
- physician assistants
- certified nurse midwives
In addition, health workers no longer need to take an eight-hour training course and apply for a federal waiver before they can prescribe buprenorphine. Previously, these requirements deterred many people from prescribing the drug.
The new guidelines also let prescribers use buprenorphine to treat up to 30 patients at a time. If they want to treat more than 30 patients, they’ll need additional training and federal waivers.
What The New Guidelines Mean For Opioid Addiction Treatment
The old guidelines made it difficult for health workers to prescribe buprenorphine. Thus, many people missed out on the medication, especially in rural areas.
Under the new guidelines, the drug will be far more accessible.
Health workers across the country will be able to prescribe it at health centers, hospitals, prisons, and other places where opioid cravings and withdrawal symptoms often cause people to relapse (start using opioids again).
Buprenorphine & Overdose Prevention
Along with preventing relapse, buprenorphine can also prevent overdose. Opioids, especially synthetic opioids like fentanyl, play a significant role in overdose deaths.
These deaths have risen with the stress of the COVID-19 pandemic.
The Centers for Disease Control and Prevention (CDC) reported about 90,000 overdose deaths between September 2019 and September 2020. This is the highest number of overdose deaths ever recorded in a 12-month period. Most involved opioids.
By expanding access to a drug that treats opioid addiction, the new guidelines could prevent numerous overdose deaths.
Buprenorphine & Addiction Stigma
Opioid addiction is like any other disease that requires medical treatment. Unfortunately, some people, including some health workers, stigmatize the condition. They often view it as a shameful inconvenience instead of a treatable disease.
In some ways, the old buprenorphine prescribing guidelines contributed to this stigma.
According to the director of the National Institute on Drug Abuse, Nora Volko, addiction is the only disease where doctors need additional training and federal waivers to prescribe a medication.
These special requirements prevent some health workers from viewing addiction like any other disease.
By making it easier to prescribe buprenorphine, the new guidelines could help health workers and other people see addiction for what it is: a disease that requires care, understanding, and prompt medical treatment.
Most addiction specialists hope the government will eventually remove other barriers to prescribing buprenorphine, including the need for training and waivers if you’re treating more than 30 patients. Still, they view the new guidelines as an important step forward.
Written by Ark Behavioral Health Editorial Team
©2025 Ark National Holdings, LLC. | All Rights Reserved.
This page does not provide medical advice.
Centers for Disease Control and Prevention - Overdose Deaths Accelerating During COVID-19
National Public Radio - As Opioid Deaths Surge, Biden Team Moves To Make Buprenorphine Treatment
National Public Radio - Why New Guidelines For Opioid Treatment Are A 'Big Deal'
Public Broadcasting Service - U.S. lifts barriers to prescribing opioid addiction treatment
U.S. Department of Health and Human Services - HHS Releases New Buprenorphine Practice Guidelines, Expanding Access to Treatment for Opioid Use Disorder
U.S. National Library of Medicine - Buprenorphine Sublingual and Buccal (opioid dependence)

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