Restoril Vs. Ambien | Differences & Similarities

Ambien (generic name zolpidem) and Restoril (generic name temazepam) are both sleeping pills that can treat sleep disorders, such as chronic insomnia.

Both drugs can treat sleeping problems, and have many similar effects. However, they are not interchangeable with each other and have several differences.

How Restoril & Ambien Work

Both prescriptions treat sleep problems by reducing brain activity, but work in slightly different ways.

Temazepam, Restoril’s main ingredient, is a benzodiazepine. It binds to benzodiazepine receptors in the central nervous system (CNS). This affects gamma-aminobutyric (GABA) receptors in the brain, which leads to decreased brain activity.

Zolpidem, Ambien’s main ingredient, is a sedative-hypnotic. Sedative-hypnotics also reduce brain activity, but are different from benzodiazepines. While benzodiazepines (such as temazepam) affect many kinds of benzodiazepine receptors, Zolpidem only affects specific types.

Ambien is available in both immediate-release and extended-release versions (Ambien CR). Restoril comes in different doses, which have the same release time.

Comparing The Effects Of Restoril & Ambien

Restoril and Ambien share some common side effects, including:

• drowsiness or sleepiness (up to the next day after taking the drug)
• dizziness
• general impairment (difficulty doing everyday tasks)

These side effects are also seen in other sleep medications, such as eszopiclone (brand name Lunesta). 

Some common side effects differ between Ambien and Restoril. Headache and nervousness are more common when taking Restoril, while diarrhea is more common when taking Ambien or Ambien CR.

Serious Side Effects

There are many reports of people doing activities after taking Restoril or Ambien, but having no memory of the activity. These activities include sleepwalking, making or eating food, or “sleep-driving.” 

People with a history of mental health problems, especially depression, may have worsened symptoms when taking sleeping pills. Depressive moods and suicidal ideations may increase when taking Restoril or Ambien.

Both Restoril and Ambien are more dangerous when mixed with other substances. Restoril, a benzodiazepine, can cause severe respiratory depression when mixed with opioids. Taking Ambien with alcohol may cause severe CNS depression.

Risks Of Restoril & Ambien Abuse

Restoril and Ambien are both Schedule IV controlled substances, according to the Drug Enforcement Administration (DEA). They are less likely to be habit-forming than other prescription drugs.

However, both drugs can cause withdrawal symptoms if you stop taking them abruptly. Withdrawal symptoms of both Restoril and Ambien include:

• lightheadedness
• vomiting
• stomach pain or cramping
• tremors (uncontrollable shaking)

These drugs share many withdrawal symptoms, due to their effects on the central nervous system.

Overdose

Both Restoril and Ambien can be dangerous when too much is taken. Overdose usually affects the CNS for both drugs.

Restoril and Ambien share many overdose symptoms, including:

• impaired state of consciousness
• respiratory depression or failure
• comatose state

Immediate medical attention is required to treat Restoril or Ambien overdose. Call for help right away if you see these signs.

Summing Up The Differences & Similarities 

Though Restoril and Ambien belong to different classes of drugs, they affect the body in many ways. They share many side effects and risks, and can both be potentially dangerous.

While they are not as habit-forming as other prescription drugs, both drugs can still cause withdrawal symptoms. Depending on the length of time you have taken Restoril or Ambien, you may experience severe withdrawal. 

To learn more about prescription drugs and possible treatments for abuse, addiction, and withdrawal, talk to your healthcare provider or contact us today.