How Long Does Klonopin (Clonazepam) Stay In Your System?

Klonopin is the brand name for a prescription drug called clonazepam. It’s used to treat seizure disorders such as epilepsy and anxiety disorders such as panic disorder.
As a central nervous system (CNS) depressant and benzodiazepine (or “benzo”), Klonopin can prevent seizures and ease anxiety by enhancing the activity of a chemical called gamma-aminobutyric acid (GABA).
Klonopin is classified as a Schedule IV controlled substance, which means it can be addictive when misused.
Like all drugs, Klonopin only stays in your system for a certain length of time.
How Long Does Klonopin Stay In Your System?
To determine how long Klonopin will stay in your system, you need to consider the drug’s half-life. Half-life is the amount of time it takes for half of a drug and its metabolites to leave your system. Metabolites are byproducts produced when your liver metabolizes (breaks down) a drug.
Klonopin is considered a long-acting benzodiazepine, as it has a long half-life of 30 to 40 hours. It usually takes about five half-lives for a drug to completely leave your system.
This means Klonopin will typically stay in your body for up to nine days after a single dose of Klonopin.
Klonopin Drug Test Detection Times
Although Klonopin will usually leave your system within nine days, the drug may show up on drug tests for a shorter period of time, and its metabolites may show up for a longer period of time, depending on the type of test.
Blood Test
In general, Klonopin and its metabolites can be detected on a blood test for about five to seven days after your last dose of Klonopin.
Urine Test
On a urine test, Klonopin’s major metabolite, 7-aminoclonazepam, can be detected for up to 30 days.
Saliva Test
Klonopin can be detected on a saliva test for up to five days. The metabolite 7-aminoclonazepam can be detected for up to six days.
However, not many people use saliva tests for detecting Klonopin, as they’re not always reliable.
Hair Follicle Test
When you ingest Klonopin, it may take days for the drug and its metabolites to appear on a hair test. Once the metabolites appear, they can remain detectable for up to 28 days.
Like saliva tests, hair follicle tests aren’t considered very reliable.
Factors That Influence Drug Detection Times
The exact amount of time Klonopin can be detected on drug tests depends on personal factors such as:
- the frequency of your Klonopin use
- how much Klonopin you’ve been using
- your age
- your weight
- your general health
- your urine concentration
If you or a loved one struggles with Klonopin abuse or addiction, please contact an Ark Behavioral Health specialist to learn about our substance abuse and addiction treatment programs.
Written by Ark Behavioral Health Editorial Team
©2025 Ark National Holdings, LLC. | All Rights Reserved.
This page does not provide medical advice.
Analytical and Bioanalytical Chemistry - Elimination of 7-aminoclonazepam in urine after a single dose of clonazepam
Journal of Analytical Toxicology - Deposition of 7-aminoclonazepam and clonazepam in hair following a single dose of Klonopin
Therapeutic Drug Monitoring - Detection Times of Diazepam, Clonazepam, and Alprazolam in Oral Fluid Collected From Patients Admitted to Detoxification, After High and Repeated Drug Intake
U.S. National Library of Medicine: MedlinePlus - Clonazepam

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