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  • Mixing Vyvanse & Magnesium | Side Effects, Risks, & Interactions

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    Mixing Vyvanse & Magnesium | Side Effects, Risks, & Interactions

    Mixing Vyvanse and magnesium together can make the effects of Vyvanse more intense. 

    You may feel severe dry mouth, constipation, anxiety, and a loss of appetite. These side effects may make Vyvanse less effective for treating attention deficit hyperactivity disorder (ADHD) or binge eating disorder.

    In severe cases, mixing Vyvanse (also known as lisdexamfetamine dimesylate) and magnesium together can cause high blood pressure, heart failure, increased body temperature, and sudden death.

    You can talk to your doctor about your family and medical history before taking Vyvanse, including any multivitamins or supplements for magnesium deficiency. 

    Side Effects Of Mixing Vyvanse & Magnesium

    If you take Vyvanse and magnesium together, you may experience more intense side effects compared to taking the drug on its own, such as:

    • trouble sleeping
    • increased heart rate
    • increased blood pressure
    • reduced brain function
    • loss of appetite
    • weight loss

    You may also experience the side effects of magnesium when taking the two substances together, such as upset stomach, diarrhea, and vomiting.

    Risks Of Mixing Vyvanse & Magnesium

    Mixing Vyvanse and magnesium can increase your risk of amphetamine toxicity. Doses of Vyvanse that are low-risk on their own can be dangerous when mixed with magnesium.

    If you or a loved one show signs of amphetamine toxicity, including psychosis, severe fatigue, and heart arrhythmia, call for help right away.

    Drug Interactions Between Vyvanse & Magnesium

    Magnesium can be an alkalinizing agent in the body, which increases the concentrations of amphetamines as they are digested. 

    By mixing magnesium with lisdexamfetamine, dextroamphetamine, and other amphetamines, you may be giving your body higher doses of amphetamines without taking higher amounts.

    Due to the risk of serious drug interactions, you may inform your doctor about magnesium supplements you are taking, such as:

    • magnesium oxide
    • magnesium citrate
    • magnesium glycinate

    These supplements may be ingredients in common multivitamins and health products. Magnesium can interact with Vyvanse similarly to monoamine oxidase inhibitor (MAOI) antidepressants, which may not be recommended for use with Vyvanse.


    What Happens When You Mix Vyvanse & Magnesium?

    When you mix Vyvanse and magnesium, you may experience serious side effects such as high blood pressure, heart arrhythmia, constipation, severe weight loss, and a spike in body temperature.

    ADHD Medication Abuse & Treatment

    Prescription drugs prescribed to treat symptoms of ADHD, such as Vyvanse, Ritalin, Adderall, and Concerta, can have a high potential for drug abuse. Mixing Vyvanse with magnesium to feel stronger stimulant effects may be a form of drug abuse.

    If you or someone you know takes Vyvanse without a prescription, or in higher doses than prescribed, your health may be at risk. Professional addiction treatment programs can help you stop taking Vyvanse safely.

    At our treatment center, our central nervous system stimulant and amphetamine abuse treatment options include drug detox, mental health health services, and behavioral therapy. To learn more, please contact us today.

    Written by Ark Behavioral Health Editorial Team
    ©2024 Ark National Holdings, LLC. | All Rights Reserved.
    This page does not provide medical advice.
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