Meth Overdose Symptoms | Can You Overdose On Meth?

Methamphetamine overdoses are unpredictable and extremely dangerous. If you suspect an overdose has occurred it’s important to stay with the victim, place them on their side in the recovery position, and immediately call for emergency medical care.
Methamphetamine (also called meth or crystal meth) is a Schedule II stimulant drug that is occasionally medically prescribed in low doses as Desoxyn, in order to treat certain conditions including narcolepsy, obesity, and attention deficit hyperactivity disorder (ADHD).
Meth increases the activity of dopamine in the synapses of the central nervous system, tripping the brain’s reward circuit and accelerating activity across the body and mind—putting both under dangerous levels of strain.
Can You Overdose on Meth?
Meth overdoses and the severe harm that they cause are, unfortunately, a persistent problem in communities across the United States.
Whether you’ve never used meth before or you’ve taken it more times than you can remember, you can overdose on meth and it may cost you your life.
The risk of overdose is increased when meth is used with other drugs, whether they be benzodiazepines, opioids, cocaine, cannabis, or alcohol.
The unpredictability involved in meth cooking also plays a role in complicating methamphetamine overdoses, as no two batches of meth will ever be the same.
One dose may be far more concentrated than another, or be cut with toxic chemicals or the powerful and overdose-prone opioid drug fentanyl.
Meth Overdose Symptoms
The signs and symptoms of a meth overdose resemble the effects experienced by those who are high on the drug, but are more extreme, as the overdose pushes your body and mental health to the brink.
Signs and symptoms of a meth overdose include:
- agitation and confusion
- chest pain or stomach pain
- difficulty breathing
- extreme changes in blood pressure
- hyperthermia
- irregular heartbeat and arrhythmia
- paranoia
- psychosis, including hallucinations or delusions
- seizures
- stroke
- unresponsiveness or coma
Death, or lasting physical harm, may occur as a result of multiple organ failure, internal bleeding, liver failure, heart attack, other cardiovascular failure or stroke.
Acute Vs. Chronic Meth Overdose
Meth overdoses can be categorized as either acute (sudden/short-term) or chronic (long-term):
- Acute overdoses occur when the drug is taken by accident or on purpose, resulting in a rapid, dangerous, and often fatal overdose condition.
- Chronic overdoses occur when meth is used over a long period of time with predictable, toxic health effects and steadily increasing dosage as tolerance develops.
Long Term Effects Of Meth Overdose
Those who survive an overdose may experience lingering health effects or permanent damage to brain and body function. Long-term effects can include:
- destruction of muscles, which can lead to amputation
- hypertension (high blood pressure)
- kidney failure that requires life-long dialysis treatment
- memory loss
- mental impairment
- seizures, stroke, and paralysis
- severe mental dysfunction including chronic anxiety and psychosis
What To Do If You Suspect A Meth Overdose
If you suspect someone around you has overdosed on meth you need to take immediate action:
- Call for medical assistance immediately and, if possible, give them the victim’s age, weight, the dosage they took, how they took it, and how long ago they took it.
- Stay with the victim and put them on their side in the recovery position. Otherwise, overdose victims may asphyxiate on their own vomit while unconscious.
- If they have a seizure do not hold them down, but try to keep their head and limbs free from solid objects. Do not put anything in their mouth.
Once medical professionals arrive they will take the patient to an emergency room for treatment, which may involve a number of tests and screenings, IV fluids, breathing support, activated charcoal, and medications to address heart, brain, muscle, or kidney issues.
Treating Methamphetamine Use
The best way to prevent meth overdose is to detox and stop using the drug altogether.
But the additive potential and physiological dependence that come from meth abuse make the drug notoriously difficult to walk away from, and the withdrawal and recovery process can be long, dangerous, and often full of setbacks.
If you or a loved one wants to overcome meth addiction, participation in a qualified inpatient addiction treatment program is your best option. To learn more, please contact Ark Behavioral Health today.
Written by Ark Behavioral Health Editorial Team
©2025 Ark National Holdings, LLC. | All Rights Reserved.
This page does not provide medical advice.
National Institute on Drug Abuse - Methamphetamine Research Report Overview
National Library of Medicine: MedlinePlus - Methamphetamine overdose
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