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  • What Is Microdosing? | Overview, Effects, Legality, & Risks

    What Is Microdosing? | Overview, Beneficial Effects, Legality, & Risks

    When most people hear the term “psychedelic drugs,” they think of intense symptoms like hallucinations (seeing, hearing, or feeling things that aren’t there) and dissociation (feeling disconnected from your body). 

    It’s true that psychedelics can make you hallucinate and dissociate. In recent years, though, some people have managed to avoid these side effects by microdosing.

    What Is Microdosing?

    Microdosing means ingesting tiny amounts of psychoactive substances, typically psychedelic substances, to achieve a sense of well-being without experiencing hallucinations, dissociation, or other extreme side effects

    A microdose, or “microgram,” is usually about one-tenth of a standard “full dose.” Microdosing schedules vary from person to person. However, many individuals take one dose every three days, typically because they find the drug’s effects last about two days.

    Common Microdosed Drugs

    The most commonly microdosed drugs are lysergic acid diethylamide (LSD) and psilocybin mushrooms (magic mushrooms or shrooms). Other drugs used in microdosing include:

    • MDMA (ecstasy or molly), a drug that functions as both a hallucinogen and a stimulant
    • N,N-dimethyltryptamine (DMT), a hallucinogenic substance found in ayahuasca, which is a psychoactive brew from South America
    • mescaline (peyote), a hallucinogenic substance found in cacti
    • phencyclidine (PCP), a drug that functions as a hallucinogen, stimulant, and painkiller
    • cannabis (marijuana)
    • methylphenidate (Ritalin), a drug used to treat attention-deficit hyperactivity disorder (ADHD)
    • nicotine, the main psychoactive ingredient in tobacco products

    Beneficial Effects Of Microdosing

    People microdose for a variety of reasons. For example, many “microdosers” seek relief from mental health concerns like depression, anxiety, bipolar disorder, schizophrenia, and addiction, especially when traditional interventions like psychotherapy and psychiatry have failed. 

    Other reported benefits of microdosing psychedelics include improved cognition, creativity, energy, sociability, and focus, as well as relief from headaches, menstrual pain, and muscle tension.

    In the past, these beneficial effects had only been recorded via anecdotal reports. More recently, psychedelic research scientists have been conducting formal microdosing studies, including double-blind clinical trials, which are considered the most reliable types of studies. 

    Studies & Research

    In a study published by the Public Library of Science, participants who took low doses of psychedelic drugs experienced:

    • decreased depression
    • decreased stress
    • improved focus

    Similar findings appeared in a 2018 questionnaire published by the journal Psychopharmacology

    Of the 1,102 participants, 44% said microdosing significantly improved their mental health, 50% said microdosing allowed them to stop taking antidepressants, and nearly 40% said microdosing allowed them to stop taking other psychiatric medications. 

    Not all studies show such promise. In a study published by the Imperial College London, for example, participants who took a placebo reported similar psychological benefits as those who took the microdose. 

    This suggests that the positive effects of microdosing may result from a placebo effect.

    Follow-up surveys and additional research studies are needed to more definitively determine the effects of microdosing. 

    Is Microdosing Legal?

    No. Psychedelic substances are illegal to produce, possess, or sell. Even if you use small doses, the drugs can appear on standard drug tests and lead to legal charges.

    However, if research continues to suggest that microdosing can have positive effects, the practice may eventually become legal. 

    Risks Of Microdosing 

    Psychedelics can cause unpleasant side effects, even at the small doses involved in microdosing. These effects may include: 

    • trouble focusing
    • fatigue
    • uncomfortable sensations
    • increased anxiety
    • neuroticism, which is a mental state characterized by negative feelings like anxiety and depression
    • psychotic symptoms, such as hallucinations, delusions, and paranoia

    Because microdosing may worsen mental health concerns like anxiety and psychosis, it might not be safe for people who already suffer from mental illnesses.

    Tolerance & Physical Dependence

    If you microdose with a non-psychedelic drug such as nicotine or Ritalin, you face the risk of addiction. 

    While most psychedelic drugs aren’t addictive, microdosing LSD and some other psychedelic drugs can lead to tolerance. Tolerance means you need increasingly or more frequent doses of a drug to feel the desired effects. 

    Also, cannabis and certain psychedelics, such as PCP, can cause physical dependence. That means your body relies on the drug to function normally. If you stop using it, you may experience unpleasant withdrawal symptoms like cravings, sweating, and headaches. 


    When you have a psychedelic experience, you may have flashbacks to it months or even years after you stop using the drug. Flashbacks make you feel like you’re reliving the experience, which some people find distressing (especially if they had an unpleasant experience, also called a “bad trip”).

    If you or someone you love struggles with psychedelic drug use, please contact an Ark Behavioral Health specialist. We offer a variety of substance abuse treatment services, including medical detox and mental health counseling, on an inpatient or outpatient basis.

    Written by Ark Behavioral Health Editorial Team
    ©2023 Ark National Holdings, LLC. | All Rights Reserved.
    This page does not provide medical advice.
    Medically Reviewed by
    Kimberly Langdon M.D.
    on July 26, 2022
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