Given its widespread use and acceptance, it’s easy to forget that alcohol is a drug. More specifically, ethanol is considered a CNS (central nervous system) depressant with psychoactive, stimulant, sedative, and toxic properties.
What Is A Central Nervous System Depressant?
CNS depressant drugs do not cause people to become depressed when they take them.
Instead, these drugs depress or reduce neurotransmitter activity in the brain, lowering physiological arousal and stimulation.
Colloquially known as downers, CNS depressants are used to calm overactive minds and bodies or generate feelings of relaxation, as with a glass of wine after a long day.
How Alcohol Functions As A Depressant
After an alcoholic beverage is consumed, the ethanol inside is absorbed into the bloodstream from the stomach and small intestine.
From there it travels to the brain and increases the activity of GABA-A receptors (structures in the brain that reduce mental and physical activity when the neurotransmitter gamma-aminobutyric acid is present) and inhibits the activity of the neurotransmitter glutamate (which increases mental and physical activity).
This CNS depression causes many of the well-known effects of alcohol inebriation, including:
- slurred speech
- impaired coordination
- slow reaction time
- impaired cognition
- impaired perception
- low blood pressure
Other CNS Depressants
The four main types of CNS depressants are:
- alcohol
- barbiturates
- benzodiazepines
- opioids
Side Effects Of Alcohol When Mixed With Other Depressants
When alcohol is mixed with other depressants there is an increased risk of dangerous CNS depression from overdose/alcohol poisoning.
This can cause symptoms that may include:
- memory loss (blacking out)
- pinpoint pupils
- inability to feel pain
- cold or bluish skin
- impaired gag reflex
- labored breathing that may develop into respiratory failure
These effects can be fatal.
How Alcohol Functions As A Stimulant
Confusingly, alcohol also has certain stimulant effects, especially within the first ninety minutes of drinking or when a large amount of alcohol is consumed quickly.
In either case, these stimulant effects are caused by dopamine, a neurotransmitter relating to pleasure and habit formation.
If enough alcohol is consumed it can trigger a dopamine release, with the level of release depending on a person’s attitude, expectations, and any mental associations they’ve built up between drinking and excitement or recreation.
This can lead to stimulant effects including:
- euphoria
- talkativeness
- increased confidence
- decreased inhibition, potentially resulting in aggressive, sexual, or risk-taking behavior
- increased heart rate
Other CNS Stimulants
Other CNS stimulants include:
- caffeine
- amphetamine
- methamphetamine
- cocaine
- and others
Alcohol Abuse
Different people drink alcohol for different reasons ranging from habit to self-medication, social lubricant, alcohol addiction, and more.
Episodic drinkers may engage in binge drinking to enjoy the stimulant effects of alcohol (often for social reasons).
Heavy drinkers drink more over a longer period of time to likely maintain the depressant effects of alcohol consumption and avoid withdrawal symptoms that develop along with alcohol dependence (often drinking alone).
Although alcohol abuse is common, professional substance abuse treatment programs offer you the resources you need to quit drinking. To learn about enrolling in our treatment centers for yourself or a loved one, please contact us today.
Written by Ark Behavioral Health Editorial Team
©2025 Ark National Holdings, LLC. | All Rights Reserved.
This page does not provide medical advice.
Centers For Disease Control and Prevention (CDC) - Alcohol Questions and Answers
National Institute on Alcohol Abuse and Alcoholism (NIAAA) - Alcohol's Effects on the Body
National Institute on Alcohol Abuse and Alcoholism (NIAAA) - Harmful Interactions

Questions About Treatment?
Ark Behavioral Health offers 100% confidential substance abuse assessment and treatment placement tailored to your individual needs. Achieve long-term recovery.
100% confidential. We respect your privacy.
Prefer Texting?
Our friendly support team is here to chat 24/7. Opt out any time.
